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Rothenfusser K
(2013) AACR Annual Meeting
two EGFR molecules need to come together to form a homodimer
Smiles: CC(C)C[C@H]([C@H](CSC1=CC=CS1)C(=O)NO)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)NC
particularly on enteric and nociceptive sensory neurons
ENMD-2076 tartrate - CAS# 1291074-87-7 lol metabolite 4-Hydroxyphenyl Carvedilol Rothenfusser KENMD 2076 is an orally active, Aurora A angiogenic kinase inhibitor with a unique kinase selectivity profile and multiple mechanisms of action. ENMD 2076 has been shown to inhibit a distinct profile of angiogenic tyrosine kinase targets in addition to the Aurora A kinase. Aurora kinases are key regulators of mitosis (cell division), and are often over expressed in human cancers. ENMD 2076 also targets the VEGFR, Flt 3 and FGFR3 kinases which have been