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Sodium carboxymethyl cellulose (MW 250000) Catalog No.:M26374-C Oclacitinib inhibits JAK family members

SKU: 17012328226

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Description

Oclacitinib inhibits JAK family members by 50% at concentrations (IC50's) ranging from 10 to 99 nM and does not inhibit a panel of 38 non-JAK kinases (IC50's >1000 nM)

and causes regenerative changes accompanied by prolonged increases in the numbers of proliferating cell nuclear antigen-positive hepatocytes in WT mice

Formula: C57H61ClFN7O9S

12 h) reduces the luciferase activity in HEK 293 cell line expressing NLUC-IRS-1 and CLUC-C14A

Kadoshima T

Sodium carboxymethyl cellulose (MW 250000) Catalog No.:M26374-C Oclacitinib inhibits JAK family membersSodium carboxymethyl cellulose (CMC Na) (MW 250000) is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent. Product information CAS Number: 9004 32 4 Molecular Weight: 262. 19 Formula: C8H15NaO8 Chemical Name: sodium 2,3,4,5,6 pentahydroxyhexanal acetate Smiles: [Na+]. CC([O ])=O. OCC(O)C(O)C(O)C(O)C=O InChiKey: QMGYPNKICQJHLN UHFFFAOYSA M InChi: InChI=1S C6H12O6. C2H4O2. Na c7 1 3(9)5(11)6(12)4(10)2

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