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RMC-5552 - CAS# 2382768-62-7 lufanide Mean body weights are significantly

SKU: 16644850022

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Description

Mean body weights are significantly higher in every group compared to that of the control

Exploration of novel VEGFR2 tyrosine kinase inhibitors via design and synthesis of new alkylated indolyl-triazole Schiff bases for targeting breast cancer

Smiles: NCC1=CNC2=CC=CC=C21

Squalamine was introduced at 20 μg/mL during HDV exposure

Formula: C36H39N3O6

RMC-5552 - CAS# 2382768-62-7 lufanide Mean body weights are significantlyRMC 5552 is a potent and selective mTORC1 inhibitor. RMC 5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0. 14 nM and 0. 48 nM, respectively. RMC 5552 shows much lower pAKT inhibition (IC50 of 19 nM), resulting in mTORC1 mTORC2 selectivity approaching 40 fold. RMC 5552 has anti cancer activity. Product information CAS Number: 2382768 62 7 Molecular Weight: 1778. 13 Formula: C93H136N10O24 Chemical Name: (1R,2R,4S) 2 methoxy 4

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