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Salirasib K474 pretreatment of the sGC reporter

SKU: 16024995947

4.2
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Description

pretreatment of the sGC reporter cell line with 10 μM ODQ for 3 h results in a significantly reduced efficacy of Vericiguat

suppresses the secretion of cholesterol and triacylglycerol and simultaneously reduces apolipoprotein B in HepG2 cells

protects against time-dependent cisplatin-induced inactivation of MTP

Significant tumor growth inhibition is observed as low as 0

Formula: C17H20F2N4O3S

Salirasib K474 pretreatment of the sGC reporterSalirasib is an inhibitor of prenylated protein methyltransferase (PPMTase) with Ki of 2. 6 M and can inhibit the methylation of Ras. Product information CAS Number: 162520 00 5 Molecular Weight: 358. 54 Formula: C22H30O2S Synonym: S Farnesylthiosalicylic acid Farnesyl Thiosalicylic Acid FTS Chemical Name: 2 (((2E,6E) 3,7,11 trimethyldodeca 2,6,10 trien 1 yl)thio)benzoic acid Smiles: CC(C)=CCC C( C)=C CC C( C)=C CSC1=CC=CC=C1C(O)=O InChiKey:

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