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RQ-00203078 Catalog No.:M18441-C InChi: InChI=1S/C16H15FN2O4/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22/h4-5

SKU: 1586368594

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Description

InChi: InChI=1S/C16H15FN2O4/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22/h4-5

Mehran Khodadoust

InChiKey: NQPCGFYLHACMDX-UHFFFAOYSA-N

demonstrates comparable pharmacodynamics and pharmacokinetics in older men and postmenopausal women

COC1=CC2CN(CCC3C=CC(=CC=3)NC(=O)C3=CC(OC)=C(C=C3NC(=O)C3=CC4=CC=CC=C4N=C3)OC)CCC=2C=C1OC

RQ-00203078 Catalog No.:M18441-C InChi: InChI=1S/C16H15FN2O4/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22/h4-5RQ 00203078 is a highly selective, potent and orally active TRPM8 antagonist with IC50s of 5. 3 nM and 8. 3 nM for rat and human TRPM8 channels, respectively. RQ 00203078 shows little inhibitory action against TRPV1, TRPA1, TRPV4, or TRPM2 channels. Product information CAS Number: 1254205 52 1 Molecular Weight: 554. 85 Formula: C21H13ClF6N2O5S Chemical Name: 4 {[3 chloro 5 (trifluoromethyl)pyridin 2 yl]({[4

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