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InChi: InChI=1S/C29H30N2O2/c1-28(2)14-15-29(3
Öztürk ZA
Exherin TFA salt
44(9):1456-66
5-dioxopyrrolidin-1-yl)oxy]-4-oxobutyl}(4-methylbenzenesulfonyl)carbamoyl)-10-(3-sulfonatopropyl)acridin-10-ium
Platensimycin e chloride hydrate InChi: InChI=1S/C29H30N2O2/c1-28(2)14-15-29(3Platensimycin is an antibiotic produced by S. platensis that inhibits gram positive bacteria by selectively inhibiting cellular lipid biosynthesis (IC50=0. 1 M). Platensimycin targets the ketoacyl acyl carrier protein synthase I II, FabF B, an enzyme that participates in the biosynthesis of fatty acids (IC50s=48 nM and 160 nM for S. aureus and E. coli enzymes, respectively). Platensimycin is a promising agent for overcoming antibiotic resistance.
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