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PubMed PMID: 26223815
InChi: InChI=1S/C30H24O12/c31-13-7-20(37)24-22(8-13)41-30(12-2-4-16(33)19(36)6-12)29(39)26(24)25-23(42-30)10-17(34)14-9-21(38)27(40-28(14)25)11-1-3-15(32)18(35)5-11/h1-8
PF04494700
OC(=O)CCC(O)=O
Epub 2017 Sep 29
GW3965 HCl - CAS# 405911-17-3 size:2mg solid PubMed PMID: 26223815GW3965 HCl, CAS No. 405911 17 3, is a liver X receptor agonist. GW3965 represses the production of pro inflammatory cytokines by murine mast cells. GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E. GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro. GW3965 dose dependently regulates lps mediated liver injury and modulates posttranscriptional TNF alpha
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