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AZD3229 is a potent
AZD-5597 exhibited excellent aqueous solubility ( > 50 mg/mL)
10 570 PMID: 25415586
13-25)19(27)28-3
and rhesus macaques with t1/2 of >8
Tivozanib (hydrate) Size:Contact [email protected] for quotation AZD3229 is a potentTivozanib, also known as AV 951 and KRN 951, is an orally active, ATP competitive, small molecule, quinoline urea derivative. Tivozanib is a pan VEGFR tyrosine kinase inhibitor. In vitro: Tivozanib markedly inhibited the ligand induced phosphorylation of VEGFR1\2 and 3 with the IC50 value of 30 nM\6. 5 nM and 15 nM, respectively. Tivozanib also exihibited inhibitory effects on PDGFR and c Ki with the IC50 value of 1. 72 and 1. 63 nmol L, respectively.