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Formula: C28H42N2O2
for 12 weeks) alleviates hepatic steatosis
InChi: InChI=1S/C25H22FNO3/c26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-19-13-18(28)14-23(29)30-19/h1-4
InChi: InChI=1S/C7H5ClF3NO2S2/c8-5-3-12-7(15-5)16(13
79183-19-0
TMC647055 Choline salt 5041 sodium Formula: C28H42N2O2TMC647055 choline salt is a cell permeating, selective HCV NS5B inhibitor, eliciting a mean IC50 of 34 nM, as assessed in the RdRp primer dependent transcription assay. IC50 value: 34 nM Target: HCV NS5Bin vitro: TMC647055 is a novel and potent nonnucleoside inhibitor of the HCV NS5B RNA dependent RNA polymerase. TMC647055 shows high selectivity for HCV when evaluated with a broad panel of human DNA and RNA viruses. TMC647055 shows median EC50 changes
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