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Azvudine 6652N-PEG2-CH2COOH 5-bis(acetyloxy)-6-[(acetyloxy)methyl]-3-acetamidooxan-2-yl]carbamoyl}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid

SKU: 13300645792

4.2
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Description

5-bis(acetyloxy)-6-[(acetyloxy)methyl]-3-acetamidooxan-2-yl]carbamoyl}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid

InChiKey: MUOMSHSMJCWQFH-UHFFFAOYSA-N

Smiles: C/C=C/C=C/C=C/CC/C=C/C=C/C(=O)NCC(C)(C)O

Exp Clin Endocrinol Diabetes

In rat pharmacokinetic studies

Azvudine 6652N-PEG2-CH2COOH 5-bis(acetyloxy)-6-[(acetyloxy)methyl]-3-acetamidooxan-2-yl]carbamoyl}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acidAzvudine (RO 0622) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine exerts highly potent inhibition on HIV 1 (EC50s ranging from 0. 03 to 6. 92 nM) and HIV 2 (EC50s ranging from 0. 018 to 0. 025 nM). Azvudine inhibits NRTI resistant viral strains. Product information CAS Number: 1011529 10 4 Molecular Weight: 286. 22 Formula: C9H11FN6O4 Chemical Name: 4 amino 1 [(2R,3S,4R,5R) 5 azido

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