Perindopril efditoren (Pivoxil) Smiles: [2H]C1C(=C([2H])C([2H])=C(F)C=1[2H])N1[C@@H]([C@@H](CC[C@H](O)C2C=CC(F)=CC=2)C1=O)C1=CC=C(O)C=C1

Smiles: [2H]C1C(=C([2H])C([2H])=C(F)C=1[2H])N1[C@@H]([C@@H](CC[C@H](O)C2C=CC(F)=CC=2)C1=O)C1=CC=C(O)C=C1

1-a]isoquinolin-2-ol

5-bis(trifluoromethyl)phenyl]-2-(H)methyl-N-methyl-N-[4-(2-methylphenyl)-6-(piperazin-1-yl)pyridin-3-yl](H)propanamide

1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic acid

Erratum in: PLoS One

Perindopril efditoren (Pivoxil) Smiles: [2H]C1C(=C([2H])C([2H])=C(F)C=1[2H])N1[C@@H]([C@@H](CC[C@H](O)C2C=CC(F)=CC=2)C1=O)C1=CC=C(O)C=C1Perindopril Erbumine is an angiotensin converting enzyme inhibitor. It is used in patients with hypertension and heart failure. Upon hydrolysis, perindopril erbumine is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II mediated vasoconstriction and angiotensin II stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis and