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TCS 2002 iclopirox InChi: InChI=1S/C25H17F3N4O3/c26-25(27

SKU: 12805955737

4.2
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Description

InChi: InChI=1S/C25H17F3N4O3/c26-25(27

Smiles: CC[C@@H]1[C@@H]2C[C@H](O)CC[C@]2(C)[C@H]2C[C@H](O)[C@]3(C)[C@H](CC[C@H]3[C@@H]2[C@@H]1O)[C@H](C)C[C@@H](C)C(O)=O

15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate

1]heptan-2-yl]-5-(2-nitrobenzoyl)-1

Chemical Name: 3-{[2-(4-fluorophenyl)ethyl]amino}-1-methyl-4-(2-methyl-1H-indol-3-yl)-2

TCS 2002 iclopirox InChi: InChI=1S/C25H17F3N4O3/c26-25(27TCS 2002 is a potent inhibitor of GSK 3 with IC50 value of 35 nM . Glycogen synthase kinase 3 (GSK 3) is a serine threonine protein kinase and functions by phosphorylating a serine or threonine residue on its target protein. GSK3 plays an important role in neuronal cell development, energy metabolism and body pattern formation. TCS 2002 is a potent GSK 3 inhibitor with IC50 value of 35 nM. (S) TCS 2002 and (R) TCS 2002 inhibited GSK 3 with IC50 values

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