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5-month-old WT and YAC128 mice over 6 weeks
a selective P2Y12-R antagonist
InChi: InChI=1S/C21H20ClN5O2/c22-14-3-1-2-13-10-15(25-16(13)14)17-18-19(23)24-8-9-27(18)20(26-17)11-4-6-12(7-5-11)21(28)29/h1-3
Damnacanthal also demonstrates modest (7-20-fold)
is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids
HMN-154 Catalog No.:M25696-C 5-month-old WT and YAC128 miceHMN 154 is a novel benzenesulfonamide anticancer compound; inhibits KB and colon38 cells with IC50 values of 0. 0026 and 0. 003 g mL, respectively. Product information CAS Number: 173528 92 2 Molecular Weight: 366. 43 Formula: C20H18N2O3S Chemical Name: 4 methoxy N {2 [(E) 2 (pyridin 4 yl)ethenyl]phenyl}benzene 1 sulfonamide Smiles: COC1C=CC(=CC=1)S(=O)(=O)NC1=CC=CC=C1 C=C C1C=CN=CC=1 InChiKey: CIJCDFMGZYKSSC VOTSOKGWSA N InChi: InChI=1S C20H18N2O3S