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InChi: InChI=1S/C20H22N2O7/c23-15-10-9-13(18(26)21-15)22-19(27)12-6-5-7-14(17(12)20(22)28)29-11-4-2-1-3-8-16(24)25/h5-7
observed clearance is 0
in the cells
it induced dramatic apoptosis in above AML cells
PIK-III acutely inhibits autophagy and de novo lipidation of LC3
Cediranib Size:2mg solid InChi: InChI=1S/C20H22N2O7/c23-15-10-9-13(18(26)21-15)22-19(27)12-6-5-7-14(17(12)20(22)28)29-11-4-2-1-3-8-16(24)25/h5-7Cediranib, also known as AZD 2171, is a potent and selective VEGF inhibitor with antineoplastic activities. Competing with adenosine triphosphate, cediranib binds to and inhibits all three vascular endothelial growth factor receptor (VEGF 1, 2, 3) tyrosine kinases, thereby blocking VEGF signaling, angiogenesis, and tumor cell growth. Product information CAS Number: 288383 20 0 Molecular Weight: 450. 51 Formula: C25H27FN4O3 Synonym: AZD2171 AZD 2171
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