Dot1L-IN-2 Size:Contact [email protected] for quotation CC1=CN=C(C[S@](=O)C2[N-]C3=CC=C(C=C3N=2)OC)C(C)=C1OC

CC1=CN=C(C[S@](=O)C2[N-]C3=CC=C(C=C3N=2)OC)C(C)=C1OC

Smiles: CC(=O)N[C@H]1CCC2=CC(OC)=C(OC)C(OC)=C2C2=CC=C(OC)C(=O)C=C21

Formula: C27H28N6O5S

and SW620 cells

CAS Number: 1427162-60-4

Dot1L-IN-2 Size:Contact [email protected] for quotation CC1=CN=C(C[S@](=O)C2[N-]C3=CC=C(C=C3N=2)OC)C(C)=C1OCDot1L IN 2 is a potent, selective and orally bioavailable inhibitor of Dot1L (a histone methyltransferase), with an IC50 and Ki of 0. 4 nM and 0. 08 nM, respectively. Product information CAS Number: 1940206 71 2 Molecular Weight: 476. 53 Formula: C27H24N8O Chemical Name: N4 methyl N2 {2 methyl 1 [2 ({3 methyl 3H imidazo[4,5 b]pyridin 6 yl}oxy)phenyl] 1H indol 6 yl}pyrimidine 2,4 diamine Smiles: