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BPTES - CAS# 314045-39-1 size:10mg solid PMA (100 nM)

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Description

PMA (100 nM)

Epub 2016 Nov 11

Formula: C16H17N5O2

Synthetic approaches to DNMT inhibitor SGI-1027 and effects on the U937 leukemia cell line

is a potent inhibitor of β-catenin-responsive transcription (CRT) that inhibits Wnt signaling in a reporter assay in vitro (IC50 = 40

BPTES - CAS# 314045-39-1 size:10mg solid PMA (100 nM)BPTES, CAS No. 314045 39 1, is a selective inhibitor of Glutaminase GLS1 (KGA), which is found in the kidney and brain, and is positively regulated by myc and strongly expressed in many tumors and tumor cell lines. BPTES has a K(i) of approx. 3 microM. BPTES inhibits the allosteric activation caused by phosphate binding and promotes the formation of an inactive complex. Product information CAS Number: 314045 39 1 Molecular Weight: 524. 68 Formula:

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