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Naratriptan Hydrochloride - CAS# 143388-64-1 Catalog No.:M10095-2 InChi: InChI=1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13(19)8-6-12/h1-9

SKU: 60100767979

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Description

InChi: InChI=1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13(19)8-6-12/h1-9

FTY720 (10 nM) alone exerts no effect on the expression of co-stimulatory molecules

and CSF-1R phosphorylation with IC50 of 2 nM

Formula: C52H76N4O12

MDL71782 hydrochloride

Naratriptan Hydrochloride - CAS# 143388-64-1 Catalog No.:M10095-2 InChi: InChI=1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13(19)8-6-12/h1-9Naratriptan is a selective 5 HT1 receptor subtype agonist for the treatment of migraine headache. Naratriptan binds with high affinity to human cloned 5 HT1B 1D receptors. Migraines are likely due to local cranial vasodilatation and or to the release of sensory neuropeptides (including substance P and calcitonin gene related peptide) through nerve endings in the trigeminal system. The therapeutic activity of AMERGE for the treatment of migraine

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