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InChiKey: NPEIWANTVUZMJV-UHFFFAOYSA-N
Peak PD responses of phospho-S6 and phospho-Akt are observed at approximately 2-4h and 1h post-administration of PF-AKT400
astrocytes and mGAT1 with the IC50 values of 2μM
4 nM) and 26 ALK resistance mutations
treatment of U-2 OS cells with Digoxin results in a dose-dependent decrease in CHIKV infection with a half-maximal effective concentration (EC50) of 48
MK-8353 Catalog No.:M19981-C InChiKey: NPEIWANTVUZMJV-UHFFFAOYSA-NMK 8353 (SCH900353) is a potent, selective and orally available ERK1 2 inhibitor, with IC50s of 23. 0 nM and 8. 8 nM, respectively; MK 8353 has antitumor activity. Product information CAS Number: 1184173 73 6 Molecular Weight: 691. 84 Formula: C37H41N9O3S Chemical Name: (3S) 1 (2 {4 [4 (1 methyl 1H 1,2,4 triazol 3 yl)phenyl] 1,2,3,6 tetrahydropyridin 1 yl} 2 oxoethyl) 3 (methylsulfanyl) N {3 [6 (propan 2 yloxy)pyridin 3 yl] 1H indazol 5 yl}pyrrolidine
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