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Pexidartinib G4-Amine demonstrating hypocholesterolemic and antiproliferative properties

SKU: 50979419989

4.1
USD80.00 USD124.00

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Description

demonstrating hypocholesterolemic and antiproliferative properties

and stiffness:665

8-trihydroxyanthraquinone

Smiles: CCS(=O)(=O)N1CCN(CC1)C1C=CC(=CC=1)NC1=NC(NC2CC2)=C(C=N1)C(N)=O

Rajkumar SV

Pexidartinib G4-Amine demonstrating hypocholesterolemic and antiproliferative propertiesPexidartinib (PLX 3397) is a potent, orally active, selective, and ATP competitive colony stimulating factor 1 receptor (CSF1R or M CSFR) and c Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX 3397) exhibits 10 to 100 fold selectivity for c Kit and CSF1R over other related kinases. Pexidartinib (PLX 3397) induces cell apoptosis and has anti tumor activity. Product information CAS Number: 1029044 16 3 Molecular Weight: 417. 81

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