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KRAS-C9 provides structure-based validation of a new allosteric regulatory site on Ras that is targetable in a mutant-specific manner
It is a synthetic auxin
Smiles: CC1C=C2C(=CC=1)N=CC(C(=O)OCC)=C2NC1C=CC(=CC=1)N(CC)CC
CAS Number: 147221-93-0
CAS Number: 1435467-37-0
TRPC6 inhibitor l Estradiol KRAS-C9 provides structure-based validation ofSAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7 mediated Ca(2+) influx into cells with IC50 s of 9. 5, 282 and 226 nM, whereas TRPC4 and TRPC5 mediated Ca(2+) entry was not affected. Product information CAS Number: 1333207 63 8 Molecular Weight: 440. 79 Formula: C21H24Cl3N3O Chemical Name: 4
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