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an irreversible EGFR TKI
6 nM in A431 cells
1182/blood-2016-02-700328
Fevipiprant reduces eosinophilic airway inflammation and is well tolerated in patients with persistent moderate-to-severe asthma and raised sputum eosinophil counts despite inhaled corticosteroid treatment
InChiKey: XIEGSJAEZIGKSA-KOQCZNHOSA-N
6-Chloro-7-deazapurine-β-D-riboside HPC-Me-CO-CH2-PEG3-NH2 an irreversible EGFR TKIChloro 7 deazapurine D riboside is a nucleoside derivative and has antifungal activity. Product information CAS Number: 16754 80 6 Molecular Weight: 285. 68 Formula: C11H12ClN3O4 Chemical Name: (2R,3R,4S,5R) 2 {4 chloro 7H pyrrolo[2,3 d]pyrimidin 7 yl} 5 (hydroxymethyl)oxolane 3,4 diol Smiles: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC2C(Cl)=NC=NC1=2 InChiKey: BFDDOTZWMOKUCD KCGFPETGSA N InChi: InChI=1S C11H12ClN3O4 c12 9 5 1 2 15(10(5)14 4 13 9)11