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c-Kit-IN-3 hydrochloride mopride InChiKey: ODRITQGYYWHQGM-UHFFFAOYSA-N

SKU: 99925448454

4.4
USD100.00 USD125.00

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Description

InChiKey: ODRITQGYYWHQGM-UHFFFAOYSA-N

c-Kit-IN-3 hydrochloride mopride InChiKey: ODRITQGYYWHQGM-UHFFFAOYSA-Nc Kit IN 3 hydrochloride (Compound 18) is a potent c KIT kinase inhibitor, which is potent and selective against BaF3 tel c KIT (IC50 of 4 nM) and a broad spectrum of drug resistant mutants (IC50 of 8 nM for BaF3 tel c KIT T670I) with improved bioavailability. c Kit IN 3 hydrochloride (Compound 18; 0. 006 M 1. 37 M) potently inhibits the growth of c KIT dependent GIST cancer cells, such as GIST T1 (IC50: 0. 006 M); GIST 882 (IC50: 0. 013 M); GIST T1

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