p38 MAPK-IN-1 xy-5 8'aS)-6'-ethyl-2-oxo-1

8'aS)-6'-ethyl-2-oxo-1

incorporates an E3 ligase ligand plus a PEG1 linker with terminal amine ready for conjugation to a target protein ligand

Activation of a novel Bcr/Abl destruction pathway by WP1130 induces apoptosis of chronic myelogenous leukemia cells

InChi: InChI=1S/C22H23F3N8O/c1-21(27)6-10-33(11-7-21)15-5-3-9-29-19(15)32-20(34)17-18(26)30-12-14(31-17)16-13(22(23

12(7):539-45

p38 MAPK-IN-1 xy-5 8'aS)-6'-ethyl-2-oxo-1p38alpha IN 4 is a reversible p38alpha MAP kinase inhibitor. Product information CAS Number: 1006378 90 0 Molecular Weight: 348. 35 Formula: C21H14F2N2O Chemical Name: 4 (2,4 difluorophenyl) 8 (2 methylphenyl) 1,7 naphthyridin 7 ium 7 olate Smiles: CC1=CC=CC=C1C1=C2N=CC=C(C3=CC=C(F)C=C3F)C2=CC=[N+]1[O ] InChiKey: BSZQSLWNMVTKJT UHFFFAOYSA N InChi: InChI=1S C21H14F2N2O c1 13 4 2 3 5 15(13)21 20 18(9 11 25(21)26)16(8 10 24 20)17 7 6 14(22)12 19(17)23 h2