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Smiles: NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
A multigram chemical synthesis of the gamma-secretase inhibitor LY411575 and its diastereoisomers
Formula: C23H19F3N8O
100%) in stimulating 5-HT2C receptor-coupled calcium mobilization and exhibits 5-HT2A receptor antagonism and 5-HT2B antagonist or partial agonist activity in transfected cells
PNT1B healthy human prostate cell proliferation is not inhibited
SR-1114 Catalog No.:M33701-C Smiles: NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12SR 1114 is a first in class PROTAC ENL degrader. SR 1114 elicits rapid, CRBN dependent degradation of ENL with DC50s of 150 nM, 311 nM, and 1. 65 M in MV4; 11 , MOLM 13, and OCI AML 2 cells, respectively. Product information CAS Number: 2769141 82 2 Molecular Weight: 830. 86 Formula: C39H42N8O11S Smiles: O=S(=O)(NC1=CC=CC(=C1)C1=CN2C=C(C=CC2=N1)C(=O)NC1CCC1)NCCOCCOCCNC(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O InChiKey: WPVVPCVQEBQVLL UHFFFAOYSA N
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