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Solamargine - CAS# 20311-51-7 Catalog No.:M9872-10 (2008) Mol Cancer Ther

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Description

(2008) Mol Cancer Ther

ADX47273 increased extracellular signal-regulated kinase and cAMP-responsive element-binding protein phosphorylation in hippocampus and prefrontal cortex

Formula: C18H13BrN4O

Safety and efficacy of tirofiban as adjunctive therapy for patients with ST-elevation myocardial infarction: a comparison versus placebo and abciximab

PubMed PMID: 23920374

Solamargine - CAS# 20311-51-7 Catalog No.:M9872-10 (2008) Mol Cancer TherSolamargine is a glycoalkaloid that has been found in S. lycocarpum and has anticancer activity. It decreases viability of H1650, H1975, PC 9, A549, and H1299 non small cell lung cancer (NSCLC) cells. Solamargine increases ERK1 2 phosphorylation and decreases the expression of DNA methyltranferase 1 (DNMT1) in H1299 and A549 cells. It reduces tumor growth and increases ERK1 2 phosphorylation and reduces the expression of the prostaglandin E2 receptor,

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