Pay in 4 interest-free payments of $14.75 Learn more
Ships within 48 hours · Estimated delivery Jul 29 - Aug 3
Molecular Weight: 379
The inhibitory effect of this agent is independent of the tumor suppressor genes VHL and p53 and may be related to derangements in glucose uptake and metabolism due to inhibition of glucose transporter-1 (Glut-1)
GSK126 is highly selective against other methyltransferases and multiple other protein classes
17 µM for CBP and ~0
Chemical Name: 4-(2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3
CB-5083 - p97 AAA ATPase Inhibitor. CAS# 1542705-92-9 0187 Molecular Weight: 379CB 5083, CAS No. 1542705 92 9, is a novel first in class, potent orally bio available p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti tumor activity in solid and hematological models . CB 5083 causes rapid and sustained accumulation of poly ubiquitin in tumor xenografts after a single administration. CB 5083 showed activity to inhibit tumor growth in multiple rodent models of human cancer. Furthermore, CB 5083 appears to
US$ 119.50
US$ 305.00
US$ 19.95
US$ 112.50
US$ 132.53
US$ 175.00