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Pharmacological stimulation of metabotropic glutamate receptor type 4 in a rat model of Parkinson's disease and L-DOPA-induced dyskinesia: Comparison between a positive allosteric modulator and an orthosteric agonist
9)10/h1-2H2
844499-71-4
Formula: C6H14N4O2
Woolley CS
Tegafur amol hemisulfate Pharmacological stimulation of metabotropic glutamateTegafur (INN) is a chemotherapeutic 5 FU prodrug used in the treatment of cancers. It is a component of tegafur uracil. When metabolized, it becomes 5 FU. T egafur uracil is a formulated therapeutic oral agent consisting of a combination of the 5 fluorouracil (5 FU) congener prodrug tegafur (tetrahydrofuranyl 5 fluorouracil) and uracil (1: 4). The high concentration of uracil reversibly inhibits the uracil reducing enzyme dihydropyrimidine