BDTX-1535 Bottles and imaging-based analysis

and imaging-based analysis

and lung adenocarcinomas

2mm Bottom Cone Bottom Length 136mm Width 98mm Height 31mm

Water/oil heating mode can be changed only through a switch

√ Handling: Aliquot to avoid repeated freeze-thaw cycles

BDTX-1535 Bottles and imaging-based analysisDescription BDTX 1535 is an orally bioavailable, brain penetrating, mutation selective, EGFR inhibitor with potential antitumor activity. BDTX 1535 is a fourth generation EGFR inhibitor that overcomes resistance to Osimertinib, the standard of care for EGFR mutant nonsmall cell lung cancer (NSCLC). BDTX 1535 works well in NSCLC carrying C797S. Importantly, BDTX 1535 can cross the blood brain barrier and potentially treat CNS metastases in NSCLC. BDTX