CDDO-dhTFEA Catalog No.:M28476-C In contrast to VRT-325 and

In contrast to VRT-325 and Corr-4a

CN(CCC1C=C(Cl)C(Cl)=CC=1)CCN1CCCC1

InChi: InChI=1S/C39H38ClN8O6S/c1-20-21(2)55-39-32(20)34(23-11-13-25(40)14-12-23)43-27(35-46-45-22(3)47(35)39)18-31(51)41-17-6-4-5-10-29(49)42-19-24-8-7-9-26-33(24)38(54)48(37(26)53)28-15-16-30(50)44-36(28)52/h7-9

SU-14813 maleate

Smiles: NC1C=CC(=CC=1)C(=O)N(CCN1CCC(CC1)C(=O)C1C=CC=CC=1)C1C=NC=CC=1

CDDO-dhTFEA Catalog No.:M28476-C In contrast to VRT-325 andCDDO dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro inflammatory transcription factor NF B. CDDO dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF B and transforming growth factor pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats. Product