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AZ20 inhibits ATR immunoprecipitated from HeLa nuclear extracts with an IC50 of 5 nM and ATR mediated phosphorylation of Chk1 in HT29 colorectal adenocarcinoma tumor cells with an IC50 of 50 nM
Y-320 inhibits IL-15-induced IL-17 production by CD4 T cells with an IC50 of 20 nM
MS-275 induces accumulation of p21WAF1/CIP1 and gelsolin in K562 cell
and the PI3K/Akt or PTEN mutational status
Chemical Name: 3-Bromo-5-phenylsalicylic acid
SJF 1528 - EGFR Degrader. CAS# 2230821-38-0 yl-N1-(pyridin-2-yl)ethane-1 2-diamine hydrochloride AZ20 inhibits ATR immunoprecipitated fromSJF 1528, EGFR Degrader, CAS No. 2230821 38 0, is a potent EGFR Degrader. It also degrades HER2. Product information CAS Number: 2230821 38 0 Molecular Weight: 1030. 60 Formula: C55H57ClFN7O8S Synonym: 1528 SJF 1528 SJF1528 Chemical Name: (2S,4R) 1 ((S) 2 (2 (2 (2 (4 (4 ((3 chloro 4 ((3 fluorobenzyl)oxy)phenyl)amino)quinazolin 6 yl)phenoxy)ethoxy)ethoxy)acetamido) 3,3 dimethylbutanoyl) 4 hydroxy N (4 (4 methylthiazol 5 yl)benzyl)pyrrolidine 2
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